(HALL PENDING)

Symposium 1.1 Epitranscriptomics and RNA editing
(Chair: Diana Guallar)

09:00 am.

• Michael Jantsch, Center of Anatomy and Cell Biology, Vienna, Austria

“From RNA-editing to smooth muscle contraction: Biomedical implications of RNA modification”

9:30 am.

• Francesca Aguiló, Wallenberg Center for Molecular Medicine, Umeå, Sweden

“The epitranscriptome: a new era for cancer research”

10:00 am.

• Diana Guallar, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Santiago de Compostela

“Diverse functions of RNA modifications in pluripotency and somatic cell reprogramming”

(HALL PENDING)

Symposium 1.2 Micropeptides
(Chair: María Abad, VHIO, Barcelona)

9:00 am.

• Juan Pablo Couso, Centro Andaluz de Biología del Desarrollo CSIC-UPO, Sevilla.

 “Small ORFs: from sequence to function”

9:30 am.

• Mar Albà. IMIM, Barcelona.

“The birth of new proteins from scratch”

10:00 am.

• Maria Abad, Vall d’Hebron Institute of Oncology (VHIO), Barcelona.

 “The microproteome as a source of novel cancer players”

(HALL PENDING)

Symposium 1.3 Novel approaches in structural biology.
(Chair: Damien Devos / Oriol Gallego)

09:00 am.

Maya Topf, Birkbeck, University of London. United Kingdom.

“Modeling protein structures in (cryo-)EM maps”

09:30 am.

• Damien Devos, Centro Andaluz de Biología del Desarrollo CSIC-UPO, Seville

“In vivo architecture of the Exocyst and beyond”

10:00 am.

• Ben Lehner, Centre for Genomic Regulation (CRG), ICREA, Barcelona

“Solving protein structures using deep mutagenesis”

(HALL PENDING)

Symposium 2.1 Cellular reprogramming beyond pluripotency
(Chair: Manuel Collado)

09:00 am.

• Manuel Collado, Health Research Institute of Santiago de Compostela, IDIS, Santiago de Compostela

“Cellular reprogramming of cancer”

09:30 am.

• Alejandro Ocampo, University of Lausanne, Lausanne, Switzerland

“Novel epigenetic approaches for the treatment of aging and disease”

10:00 am.

• Han Li, Pasteur Institute, Paris, France

“Modulating cellular plasticity in tissue regeneration”

(HALL PENDING))

Symposium 2.2 3D Genomics
(Chair: Marc Marti-Renom)

09:00 am.

• José Luis Gómez-Skarmeta, Centro Andaluz de Biología del Desarrollo CSIC-UPO, Seville

“Evolution of 3D Regulatory Landscapes”

09:30 am.

• Marc A. Marti-Renom, CNAG-CRG, Barcelona

“3DGWAS, genome-wide association studies informed by genome structure”

10:00 am.

• Jorge Ferrer, CRG & CIBERDEM, Barcelona

“3D genomics and diabetes mellitus”

(HALL PENDING)

Symposium 2.3 Biomolecular condensation
(Chair: Xavier Salvatella)

09:00 am.

• Xavier Salvatella, IRB Barcelona and ICREA Barcelona

“Biomolecular condensation as a mechanism to regulate gene expression”

09:30 am.

• Benedetta Bolognesi, IBEC, Barcelona

“Understanding Phase Transitions by Deep Mutagenesis”

10:00 am.

• Avinash Patel, Max Planck Institute for Molecular and Cellular Biology, Germany

“Biomolecular condensates for drug discovery in ALS”

(HALL PENDING)

Symposium 3.1 Chromatin plasticity and multifunctionality
(Chair: Eulàlia de Nadal)

09:00 am.

• Eulàlia de Nadal, IRB Barcelona & Pompeu Fabra University (UPF), Barcelona

“Regulation of gene expression by Stress-Activated Protein Kinases”

09:30 am.

• Biola Javierre, Josep Carreras Leukaemia Research Institute (IJC), Barcelona

 “Spatial-temporal genome architecture: understanding the contribution of non-coding variants to disease development”

10:00 am.

• Sara Sdelci, Centre for Genomic Regulation (CRG), Barcelona

 “Dissecting the ChroMetOme: an unexpected metabolism provides novel cancer vulnerabilities”

(HALL PENDING)

Symposium 3.2 The mTOR pathway in health and disease
(Chair: Alejo Efeyan)

09:00 am.

• Alejo Efeyan, Spanish National Cancer Research Center (CNIO), Madrid

“The nutrients-mTOR axis in cancer and aging”

09:30 am.

• Mario Pende, Institut Necker Enfants Malades, Inserm, Paris Sorbonne University, France

“Pathological targets of mTOR in cyst formation and seizures”

10:00 am.

• Andrea Ballabio, Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy

“A substrate-specific mTORC1 pathway mediates selective control of cell metabolism”

(HALL PENDING)

Symposium 3.3 Structural mechanisms of RNA/DNA transactions
(Chair: Rafael Fernández-Leiro)

09:00 am.

• Israel S. Fernández, Columbia University, New York, USA

“DNA targeting by a transposon encoded CRISPR/CAS system”

09: 30 am.

• Nuria Verdaguer, Molecular Biology Institute of Barcelona-CSIC, Barcelona

“The Zika virus replicase NS5 in complex with a 5’UTR RNA promoter”

10:00 am.

• Rafael Fernández Leiro, Spanish National Cancer Research Centre-CNIO, Madrid

“Capturing the elusive DNA Mismatch Repair machinery by cryo-EM”